Results

• constructed cDNA library of polyadenylated and non-polyadenylated transcripts
• sequenced and analyzed 90% of cDNA libraries
• constructed MCMV transcriptome database – to be launched upon completion of sequencing data
• confirmed that similar to HCMV; MCMV genome features antisense transcription but not so extensively as HCMV
• identified several new splice transcripts and confirmed previously published ones
• the most abundant antisense transcript is a new splice variant which appears to play a role in immunoevasion
• identified several new antisense transcripts (partially or completely overlapping known genes)
• identified a number of new miRNAs
• started in vivo studies