Activities  
Click on each Work Package to see its full description.
WP1 Upgrading the existing technological capacities of the Center for Proteomics
Objectives:
- to upgrade the Center’s infrastructure by purchasing and testing new equipment for building up a complete work flow line comprising instrumentation for:
- hybridoma development, screening and storage - upgrading of cryoconservation and storage facilities incl. data management system for large numbers of hybridoma;
- mAb and protein production and purification in high yield, including final characterization, quality assurance and function analysis;
- new protein expression techniques, e.g. automated cell free protein expression systems, including work with baculovirus vectors and insect cells as well as eukaryotic expression in mammalian cells.
Tasks:
- Purchase and establishment of equipment for optimization of hybridoma production and screening
- Establishment and testing of new equipment for mAb purification, mAb characterization and protein analysis
- Hybridoma and mAb database upgrade
- Purchase and testing of new equipment for protein expression with already existing vectors
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WP2 Recruitment of research personnel who will optimize the Center’s work-flow and disseminate its potential
Objectives:
- To employ 2 experienced postdoctoral scientists at a basis of 50% working time as research investigators, each running one team that will apply the new technologies from WP1;
- To employ one experienced postdoctoral scientist as RI at a basis of 100% working time with the responsibility for disseminating activities;
- To employ 3 lab engineers at a basis of 50 % working time who will increase the hybridoma productivity and mAb yield and who will improve protein expression and purification as well as hybridoma screening.
Tasks:
- Staff recruitment
- Expert evaluation meeting on dissemination
- Establishing at least three additional collaborative projects with innovative applications (e.g. in proteome analysis) of mAbs
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WP3 Unlocking research potential by organizing workshops and seminars or conferences
Objectives:
- To upgrade the research capacity of the Center’s research staff in frame of mAbs generation and protein analysis.
- To transfer knowledge between regional and international expert researchers.
Tasks:
- Organization of annual two-week hands-on research workshops with approximately 8 participants in the technology of generating mAbs and protein analysis, conducted by international experts
- Organization of seminars on mAb technology and application in order to facilitate knowledge transfer between regional and international experts, researchers and former workshop participants.
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WP4 Developing human resources by exchange of specific know-how in mAb development as well as protein expression and analysis
Objectives:
- To build up essential know-how in the mAb technology and protein expression field and to promote scientific development of the Center
- To exchange experience and knowledge between the Center and partner institutions in the EU and the Region in order to remain competitive.
Tasks:
- Organization of trainings for qualified research staff
- Organization of two-way short-term visits between the Center and the partner institutions in the EU and the Region
WP5 Dissemination activities
Objectives:
- To increase the visibility of the Center’s activities and goals in mAb and proteomic technology to the interested Scientific Community in general;
- To promote the Center's capabilities by showing its scientific excellence in order to attract new collaboration opportunities and service contracts, both resulting in self sustainability in the long term.
Tasks:
- Upgrade of the Center’s website
- Publishing reviews on CAPRI2010 in international research magazines
- Participation at the Festival of Science
- Organization of press conferences
- Intellectual property management establishment
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WP6 Project management
Objectives:
- To establish an administrative support to project work- and financial flow as well as formal reporting
- To establish a logistical support to conferences, workshops and travel
- To monitor the overall financial, administrative, legal and ethical aspects of the project including contracting with the EU authorities
- To organize external audits in order to assess CAPRI2010 financial statements
Tasks:
- Planning of specific (e.g. networking) activities to increase the Center’s research potential; organization and coordination of human and material resources, recruitment and motivation of the selected personnel, control of the financial flow of the project, communication with the internal and external stakeholders.
- Maintenance of the web-page, organization of workshops and training seminars, advertisements in international scientific publications, public relations, communication with the partner institutions of the project.
- Financial management of the project, including periodic, mid-term and final reports, with a special emphasis on financial aspect of the reports.
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